Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779393 | 1.00 | ERAP2 (0.56) | ERAP2IL1RNERAP1LNPEPSMN1; SMN2 | |
| SCHEMBL28270209 | 0.96 | ERAP2 (0.55) | ERAP2IL1RNERAP1LNPEPSMN1; SMN2 | |
| SCHEMBL28270210 | 0.96 | ERAP2 (0.55) | ERAP2IL1RNERAP1LNPEPSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7325792 | 0.91 | CTSB (0.51) | ERAP2IL1RNERAP1LNPEPCTSB | |
| SCHEMBL13044203 | 0.90 | IL1RN (0.56) | ERAP2IL1RNERAP1SMN1; SMN2CTSB | |
| SCHEMBL28252260 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1ASAH1 | |
| SCHEMBL19388178 | 0.87 | IL1RN (0.54) | ERAP2IL1RNERAP1SMN1; SMN2CTSB | |
| SCHEMBL28252259 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1ASAH1 | |
| SCHEMBL3564467 | 0.87 | KMT2A (0.47) | ERAP2IL1RNERAP1LNPEPPOLB | |
| SCHEMBL11913993 | 0.86 | IL1RN (0.58) | ERAP2IL1RNERAP1CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943794-B2 | Processes for the preparation of intermediates of valsartan | RANBAXY LABORATORIES LIMITED (IN) | 2011-05-17 | — | — | US | disclosed |
| EP-2090567-A2 | Processes for the preparation of intermediates of valsartan | RANBAXY LABORATORIES, LTD. (IN) | 2009-08-19 | — | — | EP | disclosed |
| US-20090203921-A1 | PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF VALSARTAN | RANBAXY LABORATORIES LIMITED (IN) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203921-A1 | PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF VALSARTAN | REN, AGT, ACE | ERAP2 343/4885IL1RN 1355/4885ERAP1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.