Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | SDCBP | O00560 | 1/20 | 0.45 |
| ▸ | SDC2 | P34741 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779393 | 0.87 | ERAP2 (0.56) | KMT2AERAP2IL1RNERAP1POLB | |
| SCHEMBL1779398 | 0.87 | ERAP2 (0.56) | KMT2AERAP2IL1RNERAP1POLB | |
| SCHEMBL28270209 | 0.84 | ERAP2 (0.55) | KMT2AERAP2IL1RNERAP1LNPEP | |
| SCHEMBL28270210 | 0.84 | ERAP2 (0.55) | KMT2AERAP2IL1RNERAP1LNPEP | |
| SCHEMBL30574529 | 0.80 | CTSB (0.43) | KMT2AERAP2IL1RNERAP1MAPT | |
| Hydrochloric Acid SCHEMBL7325792 | 0.79 | CTSB (0.51) | KMT2AERAP2IL1RNERAP1LNPEP | |
| SCHEMBL28291704 | 0.78 | HDAC1 (0.58) | KMT2AHDAC1HDAC6SDCBPSDC2 | |
| SCHEMBL28579332 | 0.77 | CTSB (0.41) | KMT2AERAP2IL1RNERAP1MAPT | |
| SCHEMBL28585493 | 0.77 | CTSB (0.41) | KMT2AERAP2IL1RNERAP1MAPT | |
| SCHEMBL13044203 | 0.77 | IL1RN (0.56) | KMT2AERAP2IL1RNERAP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728021-B2 | Process for the preparation of Valsartan and precursors thereof | INKE, S.A. (ES) | 2010-06-01 | — | — | US | disclosed |
| US-20090221836-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND PRECURSORS THEREOF | INKE, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221836-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND PRECURSORS THEREOF | REN, AGT, NPPA | KMT2A 3473/4885HDAC1 2159/4885HDAC6 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.