Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 20/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177948 | 0.87 | FDPS (0.66) | FDPSPDE3AGGPS1LMNAADRB3 | |
| Olpadronic Acid SCHEMBL7457593 | 0.87 | FDPS (0.71) | FDPSPDE3AGGPS1AGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL9581942 | 0.77 | FDPS (0.69) | FDPSPDE3AGGPS1AGTR1OPRM1 | |
| SCHEMBL6669236 | 0.76 | FDPS (0.63) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL2178802 | 0.76 | FDPS (0.63) | FDPSPDE3AGGPS1LMNAADRB3 | |
| Olpadronic Acid SCHEMBL138988 | 0.75 | FDPS (0.58) | FDPSPDE3AGGPS1AGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL232124 | 0.74 | FDPS (0.56) | FDPSPDE3AGGPS1AGTR1OPRM1 | |
| Alendronic Acid SCHEMBL18898 | 0.73 | FDPS (1.00) | FDPSPDE3AGGPS1LMNAADRB3 | |
| Alendronic Acid SCHEMBL6270347 | 0.73 | FDPS (1.00) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL8050464 | 0.73 | FDPS (0.68) | FDPSPDE3AGGPS1LMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943155-B2 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-13 | — | — | US | claimed |