Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556580 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CYP2D6HRH3CNR1FAAH | |
| SCHEMBL17805278 | 0.90 | MC4R (0.46) | CNR1FAAHMC4RKDM4EALDH1A1 | |
| SCHEMBL30577958 | 0.90 | MC4R (0.46) | CNR1FAAHMC4RKDM4EALDH1A1 | |
| SCHEMBL1252458 | 0.90 | MC4R (0.46) | CNR1FAAHMC4RKDM4EALDH1A1 | |
| SCHEMBL19600508 | 0.89 | ALDH1A1 (0.37) | SIGMAR1CYP2D6HRH3CNR1KDM4E | |
| SCHEMBL17805293 | 0.87 | BCHE (0.47) | HRH3KDM4EHSD17B10ADORA2AALDH1A1 | |
| SCHEMBL23616077 | 0.86 | MC4R (0.41) | CNR1FAAHMC4RKDM4EADORA2A | |
| SCHEMBL19605798 | 0.84 | HRH4 (0.42) | CNR1FAAHMC4RKDM4E | |
| SCHEMBL21044241 | 0.84 | MC4R (0.41) | CNR1FAAHMC4RKDM4EALDH1A1 | |
| SCHEMBL30218430 | 0.84 | MC4R (0.41) | CNR1FAAHMC4RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909948-B1 | BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2024-02-28 | — | — | EP | claimed |
| US-20220143230-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-05-12 | — | — | US | claimed |
| US-11266754-B2 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-03-08 | — | — | US | claimed |
| EP-3909948-A1 | BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-11-17 | — | — | EP | claimed |
| EP-3227272-B1 | BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2021-07-07 | — | — | EP | claimed |
| US-20200038527-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2020-02-06 | — | — | US | claimed |
| US-20170326261-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-16 | — | — | US | claimed |
| EP-3227272-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | Centre National de la Recherche Scientifique (CNRS) (FR) | 2017-10-11 | — | — | EP | claimed |
| WO-2016087667-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-06-09 | — | — | WO | claimed |
| EP-3029032-A1 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-06-08 | — | — | EP | claimed |
| EP-3909948-B1 | BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2024-02-28 | — | — | EP | disclosed |
| EP-3909948-B1 | BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2024-02-28 | — | — | EP | disclosed |
| US-20220143230-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-05-12 | — | — | US | disclosed |
| US-20220143230-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-05-12 | — | — | US | disclosed |
| US-11266754-B2 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-03-08 | — | — | US | disclosed |
| US-20170326261-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170326261-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-16 | — | — | US | disclosed |
| WO-2016087667-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-06-09 | — | — | WO | disclosed |
| EP-3029032-A1 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029032-A1 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038527-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | AP2A2, ATP2A2, SLC20A2 | SIGMAR1 271/4885CYP2D6 133/4885HRH3 1008/4885 |
| US-20220143230-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | AP2A2, ATP2A2, SLC20A2 | SIGMAR1 271/4885CYP2D6 133/4885HRH3 1008/4885 |
| US-20170326261-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | AP2A2, ATP2A2, SLC20A2 | SIGMAR1 271/4885CYP2D6 133/4885HRH3 1008/4885 |
| US-11266754-B2 | Bifunctional do2pa derivatives, chelates with metallic cations and use thereof | AP2A2, ATP2A2, SLC20A2 | SIGMAR1 271/4885CYP2D6 133/4885HRH3 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.