Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797222 | 0.93 | PYGL (0.35) | PYGLACLYPIK3R1PIK3CACYP1A2 | |
| SCHEMBL2470016 | 0.93 | PYGL (0.35) | PYGLACLYPIK3R1PIK3CACYP1A2 | |
| SCHEMBL17797257 | 0.91 | PIK3R1 (0.33) | PYGLPIK3R1PIK3CACYP1A2ALDH1A1 | |
| SCHEMBL17797234 | 0.90 | RORC (0.37) | CYP1A2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL17797201 | 0.90 | PIK3R1 (0.33) | PIK3R1PIK3CACYP1A2HSD17B10ADORA3 | |
| SCHEMBL17797196 | 0.87 | ALDH1A1 (0.33) | PYGLALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL17797199 | 0.87 | CYP1A2 (0.34) | PYGLACLYPIK3R1PIK3CACYP1A2 | |
| SCHEMBL17797245 | 0.87 | ALDH1A1 (0.35) | PIK3R1PIK3CACYP1A2ALDH1A1HPGD | |
| SCHEMBL3840578 | 0.86 | ACLY (0.36) | PYGLACLYCYP1A2ALDH1A1HPGD | |
| SCHEMBL17797238 | 0.85 | ALDH1A1 (0.32) | PYGLALDH1A1HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |