Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469998 | 0.92 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1PDCD1LG2CD274GRK6 | |
| SCHEMBL2462793 | 0.90 | PDCD1LG2 (0.35) | HSP90AA1HSP90AB1PDCD1LG2CD274FRK | |
| SCHEMBL3836838 | 0.83 | MAPK1 (0.37) | HSP90AA1HSP90AB1GRK6MAPK1RAB9A | |
| SCHEMBL2465821 | 0.82 | CTSA (0.37) | KMT2A | |
| SCHEMBL2465963 | 0.82 | MAPK9 (0.35) | HSP90AB1MAPK1RAB9ALMNAHTT | |
| SCHEMBL2467937 | 0.82 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1PDCD1LG2CD274RAB9A | |
| SCHEMBL17797261 | 0.81 | PDCD1LG2 (0.40) | HSP90AA1HSP90AB1PDCD1LG2CD274 | |
| SCHEMBL2468802 | 0.81 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1LMNAHTTKMT2A | |
| SCHEMBL17797218 | 0.81 | PDCD1LG2 (0.37) | HSP90AA1HSP90AB1PDCD1LG2CD274 | |
| SCHEMBL2469714 | 0.80 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1MAPK1LMNAMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |