Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469714 | 0.87 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1LMNAHPGDKMT2A | |
| SCHEMBL2466531 | 0.86 | CYP2D6 (0.47) | HSP90AA1HSP90AB1ADORA3LMNAHPGD | |
| SCHEMBL2469200 | 0.85 | PRKDC (0.39) | ATRADORA1ADORA2ALMNAHPGD | |
| SCHEMBL2464096 | 0.85 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ATRADORA1ADORA2A | |
| SCHEMBL2467530 | 0.82 | ADORA2A (0.40) | ADORA3ATRADORA1ADORA2AVCP | |
| SCHEMBL2468801 | 0.82 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1ADORA3ATRADORA1 | |
| SCHEMBL2470000 | 0.82 | ACHE (0.45) | HSP90AA1HSP90AB1ADORA3ADORA1ADORA2A | |
| SCHEMBL17797243 | 0.81 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1LMNAKMT2AHTT | |
| SCHEMBL2468353 | 0.81 | MEN1 (0.52) | ADORA3ADORA1DHODHADORA2AHPGD | |
| SCHEMBL2468243 | 0.81 | ALDH1A1 (0.38) | HSP90AA1HSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |