Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 13/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797218 | 0.94 | PDCD1LG2 (0.37) | PDCD1LG2CD274PTPN11HSP90AA1HSP90AB1 | |
| SCHEMBL2467890 | 0.90 | PDCD1LG2 (0.39) | PDCD1LG2CD274PTPN11 | |
| SCHEMBL2467541 | 0.88 | ALDH1A1 (0.37) | PDCD1LG2CD274HSP90AA1HSP90AB1 | |
| SCHEMBL2468243 | 0.88 | ALDH1A1 (0.38) | PDCD1LG2CD274HSP90AA1HSP90AB1KMO | |
| SCHEMBL2468810 | 0.86 | PDCD1LG2 (0.33) | PDCD1LG2CD274PTPN11HSP90AA1HSP90AB1 | |
| SCHEMBL2462590 | 0.86 | ALOX5AP (0.35) | PDCD1LG2CD274HSP90AA1HSP90AB1 | |
| SCHEMBL17797244 | 0.85 | PDCD1LG2 (0.36) | PDCD1LG2CD274 | |
| SCHEMBL2470475 | 0.85 | ALOX5AP (0.46) | PDCD1LG2CD274 | |
| SCHEMBL17797209 | 0.84 | MAPK9 (0.37) | PDCD1LG2CD274KMO | |
| SCHEMBL2469711 | 0.84 | CYP3A4 (0.34) | PDCD1LG2CD274KMOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |