Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 7/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467541 | 0.93 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10PDCD1LG2CD274 | |
| SCHEMBL2470407 | 0.89 | PDCD1LG2 (0.38) | ALDH1A1KDM4EHSD17B10ALPLPDCD1LG2 | |
| SCHEMBL17797261 | 0.88 | PDCD1LG2 (0.40) | PDCD1LG2CD274HSP90AA1HSP90AB1KMO | |
| SCHEMBL2462590 | 0.88 | ALOX5AP (0.35) | HSD17B10PDCD1LG2CD274HSP90AA1HSP90AB1 | |
| SCHEMBL2465856 | 0.88 | PPARA (0.36) | ALDH1A1KDM4EALPLPDCD1LG2CD274 | |
| SCHEMBL17797244 | 0.85 | PDCD1LG2 (0.36) | PDCD1LG2CD274 | |
| SCHEMBL17797218 | 0.85 | PDCD1LG2 (0.37) | PDCD1LG2CD274HSP90AA1HSP90AB1 | |
| SCHEMBL2468810 | 0.84 | PDCD1LG2 (0.33) | PDCD1LG2CD274HSP90AA1HSP90AB1 | |
| SCHEMBL2469721 | 0.83 | ALPL (0.32) | ALPLPDCD1LG2CD274 | |
| SCHEMBL2470475 | 0.83 | ALOX5AP (0.46) | HSD17B10PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |