Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781134 | 1.00 | ROCK2 (0.51) | ROCK2ROCK1ALDH1A1LMNAMAPK1 | |
| SCHEMBL27490296 | 0.79 | ROCK1 (0.60) | ROCK2ROCK1ALDH1A1LMNAMAPK1 | |
| SCHEMBL2158149 | 0.76 | HPGD (0.51) | ALDH1A1LMNAPOLBHPGDKDM4E | |
| SCHEMBL8261087 | 0.76 | ROCK2 (0.47) | ROCK2ROCK1ALDH1A1LMNAPOLB | |
| SCHEMBL14329840 | 0.74 | MAPT (0.61) | ALDH1A1MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL21756727 | 0.72 | NPC1 (0.52) | ROCK2ROCK1ALDH1A1LMNAMAPK1 | |
| SCHEMBL21756726 | 0.72 | NPC1 (0.52) | ROCK2ROCK1ALDH1A1LMNAMAPK1 | |
| SCHEMBL21756730 | 0.72 | NPC1 (0.52) | ROCK2ROCK1ALDH1A1LMNAMAPK1 | |
| SCHEMBL16348943 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNAPOLBHPGDKDM4E | |
| SCHEMBL12461860 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNAPOLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178148-A1 | SUBSTITUTED 5-VINYLPHENYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-07-21 | — | — | US | disclosed |
| US-7943653-B2 | Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178148-A1 | SUBSTITUTED 5-VINYLPHENYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, GPR18 | ROCK2 4025/4885ROCK1 3522/4885ALDH1A1 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.