Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293118 | 0.64 | CES2 (0.52) | THRBTSHRCES2CTSLCTSB | |
| SCHEMBL31718131 | 0.64 | TSHR (0.50) | THRBTSHRCES2CTSLCTSB | |
| Octane SCHEMBL26632661 | 0.64 | — | — | |
| SCHEMBL25022297 | 0.64 | TSHR (0.50) | THRBTSHRCES2CTSLCTSB | |
| SCHEMBL17429830 | 0.64 | TSHR (0.50) | THRBTSHRCES2CTSLCTSB | |
| SCHEMBL31138853 | 0.64 | TSHR (0.42) | THRBTSHRHSD17B10DNM1EPHX1 | |
| SCHEMBL199047 | 0.63 | THRB (0.57) | THRBTSHRCES2CTSLCTSB | |
| Dioctylsulfane SCHEMBL23901 | 0.63 | THRB (0.57) | THRBTSHRCES2CTSLCTSB | |
| SCHEMBL24362145 | 0.63 | THRB (0.57) | THRBTSHRCES2CTSLCTSB | |
| SCHEMBL20634256 | 0.63 | TSHR (0.57) | THRBTSHRCES2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722835-B2 | One component polysiloxane coating compositions and related coated substrates | PPG INDUSTRIES OHIO, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2665789-A1 | ONE COMPONENT POLYSILOXANE COATING COMPOSITIONS AND RELATED COATED SUBSTRATES | PPG Industries Ohio, Inc. (US) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012100140-A1 | ONE COMPONENT POLYSILOXANE COATING COMPOSITIONS AND RELATED COATED SUBSTRATES | PPG INDUSTRIES OHIO, INC. (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20110118406-A1 | ONE COMPONENT POLYSILOXANE COATING COMPOSITIONS AND RELATED COATED SUBSTRATES | PPG IDUSTRIES OHIO, INC. (US) | 2011-05-19 | — | — | US | disclosed |