Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | PRKCG | P05129 | 2/20 | 0.41 |
| ▸ | PRKCB | P05771 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774957 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL10776914 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL199114 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL10607304 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL10773852 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL8772624 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL10771398 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL387424 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL16622483 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL386145 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | claimed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | claimed |
| JP-2003509485-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | claimed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | claimed |
| EP-3476218-A1 | FATTY ACID CONJUGATES OF QUETIAPINE, PROCESS FOR MAKING AND USING THE SAME | Kempharm, Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-2544536-B1 | FATTY ACID CONJUGATES OF QUETIAPINE, PROCESS FOR MAKING AND USING THE SAME | KEMPHARM INC (US) | 2018-12-12 | — | — | EP | disclosed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| EP-1218000-A4 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
| EP-1218000-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021172-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | CES2 3339/4885THRB 480/4885GMNN 3994/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | CES2 1752/4885THRB 541/4885GMNN 4244/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | CES2 3396/4885THRB 207/4885GMNN 3428/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | CES2 1752/4885THRB 541/4885GMNN 4244/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | CES2 1519/4885THRB 552/4885GMNN 4491/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | CES2 1752/4885THRB 541/4885GMNN 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.