SCHEMBL17799677

SCHEMBL17799677

O=C(N[C@H]1CC[C@H]1c1ccc(Cl)cc1)c1sccc1Br

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FPR1 P21462 3/20 0.39
▸ AKT1 P31749 13/20 0.39
▸ FPR2 P25090 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ AGTR1 P30556 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ GRIA4 P48058 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17799671 0.88 GAA (0.50) FPR1AKT1FPR2ALDH1A1GAA
SCHEMBL17799658 0.84 FPR1 (0.37) FPR1AKT1FPR2NPC1RAB9A
SCHEMBL17799697 0.83 NPC1 (0.40) ALDH1A1GAAMAPTAGTR1TDP1
SCHEMBL17799650 0.81 FPR1 (0.38) FPR1AKT1FPR2GRIA4NPC1
SCHEMBL17799740 0.79 FPR1 (0.37) FPR1AKT1FPR2GRIA4NPC1
SCHEMBL17799635 0.78 L3MBTL1 (0.46) FPR1FPR2ALDH1A1MEN1NPC1
SCHEMBL17799687 0.77 AKT1 (0.38) FPR1AKT1FPR2
SCHEMBL20298565 0.75 AKT1 (0.38) FPR1AKT1FPR2
SCHEMBL17799735 0.74 LMNA (0.54) ALDH1A1GAAMAPTNPC1RAB9A
SCHEMBL17799721 0.74 HCRTR1 (0.47) FPR1AKT1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 — — US disclosed
EP-3019476-B1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 — — EP disclosed
US-9867371-B2 4-membered ring carboxamides used as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2018-01-16 — — US disclosed
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES TUBA3C, DDT, CYCS FPR1 605/4885AKT1 4061/4885FPR2 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback