SCHEMBL17799753

SCHEMBL17799753

O=C(N[C@H]1CC[C@H]1c1ccc(F)cc1F)c1sccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ GAA P10253 5/20 0.39
▸ PKM P14618 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ FPR1 P21462 5/20 0.39
▸ FPR2 P25090 4/20 0.39
▸ ALDH1A1 P00352 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ GSK3A P49840 1/20 0.37
▸ GSK3B P49841 1/20 0.37
▸ MC1R Q01726 2/20 0.37
▸ HCRTR1 O43613 2/20 0.37
▸ MAPT P10636 1/20 0.36
▸ AGTR1 P30556 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17799696 0.87 ALDH1A1 (0.38) RAB9AGAAFPR1FPR2ALDH1A1
SCHEMBL17799722 0.84 HPGD (0.41) RAB9AHPGDFPR1FPR2MC1R
SCHEMBL17799645 0.82 GAA (0.44) F10RAB9AGAAPKMALDH1A1
SCHEMBL17799691 0.80 TSHR (0.56) RAB9AGAAPKMHPGDALDH1A1
SCHEMBL17799701 0.80 TAS1R3 (0.39) HPGDFPR1FPR2MC1RHCRTR1
SCHEMBL17799747 0.80 TAS1R3 (0.39) RAB9AHPGDFPR1FPR2MC1R
SCHEMBL17799672 0.79 GAA (0.56) RAB9AGAAPKMALDH1A1KMT2A
SCHEMBL17799733 0.79 HCRTR1 (0.50) F10RAB9AGAAPKMHPGD
SCHEMBL20298551 0.77 MC1R (0.37) RAB9AFPR1FPR2KMT2AMC1R
SCHEMBL17799700 0.77 HCRTR1 (0.49) GAAPKMFPR1FPR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 — — US disclosed
EP-3019476-B1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 — — EP disclosed
US-9867371-B2 4-membered ring carboxamides used as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2018-01-16 — — US disclosed
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES TUBA3C, DDT, CYCS F10 4392/4885RAB9A 1776/4885GAA 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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