SCHEMBL17799722

SCHEMBL17799722

O=C(N[C@H]1CC[C@H]1c1ccc(F)cc1F)c1ccsc1Cl

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.41
▸ TAS1R3 Q7RTX0 1/20 0.39
▸ TAS1R1 Q7RTX1 1/20 0.39
▸ TAS1R2 Q8TE23 1/20 0.39
▸ FPR1 P21462 5/20 0.39
▸ FPR2 P25090 4/20 0.39
▸ HCRTR1 O43613 3/20 0.36
▸ HCRTR2 O43614 2/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ MC1R Q01726 3/20 0.35
▸ RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17799747 0.86 TAS1R3 (0.39) HPGDTAS1R3TAS1R1TAS1R2FPR1
SCHEMBL17799701 0.86 TAS1R3 (0.39) HPGDTAS1R3TAS1R1TAS1R2FPR1
SCHEMBL17799753 0.84 F10 (0.39) HPGDFPR1FPR2HCRTR1MC1R
SCHEMBL17799733 0.81 HCRTR1 (0.50) HPGDTAS1R3TAS1R1TAS1R2HCRTR1
SCHEMBL17799737 0.81 RAB9A (0.46) TAS1R3TAS1R1TAS1R2HCRTR2RAB9A
SCHEMBL17799696 0.81 ALDH1A1 (0.38) TAS1R3TAS1R1TAS1R2FPR1FPR2
SCHEMBL17799691 0.80 TSHR (0.56) HPGDL3MBTL1RAB9A
SCHEMBL17799692 0.80 HCRTR1 (0.49) TAS1R3TAS1R1TAS1R2HCRTR1HCRTR2
SCHEMBL17799632 0.78 EGFR (0.46) HPGDTAS1R3TAS1R1TAS1R2FPR1
SCHEMBL31622401 0.78 HPGD (0.43) HPGDTAS1R3TAS1R1TAS1R2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 — — US disclosed
EP-3019476-B1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 — — EP disclosed
US-9867371-B2 4-membered ring carboxamides used as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2018-01-16 — — US disclosed
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES TUBA3C, DDT, CYCS HPGD 1934/4885TAS1R3 3195/4885TAS1R1 3418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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