Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079306 | 0.81 | NPC1 (0.41) | DGAT2 | |
| SCHEMBL18548025 | 0.78 | DGAT2 (0.40) | DGAT2MAPK1 | |
| SCHEMBL17801061 | 0.75 | KMT2A (0.38) | DGAT2MAPT | |
| SCHEMBL22160453 | 0.74 | CYP4F2 (0.39) | — | |
| SCHEMBL5378173 | 0.74 | RAB9A (0.41) | MAPTMAPK1 | |
| SCHEMBL30182911 | 0.74 | MAPT (0.38) | DGAT2MAPTMAPK1 | |
| SCHEMBL29363550 | 0.74 | MAP3K5 (0.37) | DGAT2 | |
| SCHEMBL17801031 | 0.73 | CNR2 (0.35) | DGAT2 | |
| SCHEMBL30950223 | 0.72 | CYP4F2 (0.39) | DGAT2MAPTMAPK1 | |
| SCHEMBL20030949 | 0.72 | RXRA (0.36) | DGAT2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089977-A1 | SUBSTITUTED INDAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |