Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428229 | 0.81 | GNAI3 (0.34) | CCNT1CDK9TSHRL3MBTL1GAA | |
| SCHEMBL13403908 | 0.79 | HCRTR2 (0.38) | CCNT1CDK9TSHRL3MBTL1GAA | |
| SCHEMBL13301197 | 0.78 | HSD11B1 (0.38) | CCNT1CDK9TSHRL3MBTL1JAK1 | |
| SCHEMBL13816965 | 0.77 | ALDH1A1 (0.39) | TSHRL3MBTL1GAAKMT2ATP53 | |
| SCHEMBL13301165 | 0.77 | ALDH1A1 (0.42) | TSHRL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL18024028 | 0.75 | ALDH1A1 (0.45) | TSHRL3MBTL1GAANPSR1KMT2A | |
| SCHEMBL11936225 | 0.74 | SMN1; SMN2 (0.38) | TSHRL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL8281581 | 0.72 | CA12 (0.48) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL25541434 | 0.72 | KDM4E (0.42) | TSHRMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL429660 | 0.70 | TP53 (0.48) | TSHRL3MBTL1GAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |