SCHEMBL17801580

SCHEMBL17801580

Fc1ccc(OCOc2ccc(F)cc2I)c(I)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.37
KLK1 P06870 1/20 0.35
TRPA1 O75762 1/20 0.35
F2 P00734 1/20 0.34
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15065521 0.87 CYP1A2 (0.39) PKMKLK1TRPA1F2
SCHEMBL20516081 0.85 F2 (0.44) PKMF2
SCHEMBL725628 0.85 F2 (0.41) PKMF2
SCHEMBL22138659 0.83 L3MBTL1 (0.44)
SCHEMBL4359101 0.83 PKM (0.35) PKMKLK1TRPA1F2APP
SCHEMBL29469907 0.83 L3MBTL1 (0.44)
SCHEMBL17861666 0.80 PKM (0.37) PKMTRPA1F2
SCHEMBL18857831 0.80 PKM (0.33) PKMKLK1TRPA1F2
SCHEMBL28448358 0.80 HTR2C (0.48)
SCHEMBL15847648 0.79 F2 (0.37) PKMF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107041138-B Pentacomplex bisphenylphenoxy catalyst for preparing vinyl polymer 陶氏环球技术有限责任公司 2020-11-27 CN disclosed
EP-3227304-B1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-29 EP disclosed
EP-3227304-B1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-29 EP disclosed
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-28 US disclosed
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-28 US disclosed
EP-3227304-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS Dow Global Technologies LLC (US) 2017-10-11 EP disclosed
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-09-21 US disclosed
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-09-21 US disclosed
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-09-21 US disclosed
WO-2016089935-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-09 WO disclosed
WO-2016089935-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS PARG, AP1M1, BZW1 PKM 28/4885KLK1 2200/4885TRPA1 2540/4885
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers PARG, AP1M1, BZW1 PKM 28/4885KLK1 2200/4885TRPA1 2540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.