Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507691 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TRPA1ACP3 | |
| SCHEMBL10554772 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3TRPA1ACP3 | |
| SCHEMBL28620633 | 0.83 | CALM1 (0.46) | SLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL3398678 | 0.82 | IGF1R (0.57) | SLC6A2SLC6A4SLC6A3IGF1RCNR2 | |
| SCHEMBL17802382 | 0.81 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3CNR2MEN1 | |
| SCHEMBL17802381 | 0.81 | PPARG (0.45) | SLC6A4SLC6A3CNR2CYP19A1TRPA1 | |
| SCHEMBL11604717 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3IGF1RCYP19A1 | |
| SCHEMBL5982885 | 0.76 | SLC18A3 (0.53) | IGF1RMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28624377 | 0.75 | LTA4H (0.52) | — | |
| SCHEMBL108646 | 0.75 | TRPA1 (0.58) | SLC6A2SLC6A4SLC6A3TRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016088138-A1 | DIPHENYLOXIRANES, PROCESS FOR PREPARATION THEREOF, AND ITS USE IN AN ENANTIOSELECTIVE SYNTHESIS OF (+)-SERTRALINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-09 | — | — | WO | disclosed |