SCHEMBL28620633

SCHEMBL28620633

OC(Cc1ccc(Cc2ccccc2)cc1)C(O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.46
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
TRPA1 O75762 1/20 0.43
IDH1 O75874 1/20 0.41
SLC6A2 P23975 6/20 0.40
SLC6A4 P31645 6/20 0.40
SLC6A3 Q01959 6/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.39
KCNH2 Q12809 1/20 0.39
SLC22A2 O15244 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10554772 0.88 SLC6A2 (0.50) TRPA1SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL11507691 0.88 SLC6A2 (0.50) TRPA1SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL17802415 0.83 SLC6A2 (0.53) TRPA1SLC6A2SLC6A4SLC6A3
SCHEMBL17802381 0.83 PPARG (0.45) PPARGPPARATRPA1SLC6A4SLC6A3
SCHEMBL17802382 0.83 SLC6A4 (0.53) PPARGPPARATRPA1SLC6A2SLC6A4
SCHEMBL27426168 0.81 ESR1 (0.46) SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6
SCHEMBL28624377 0.80 LTA4H (0.52) PPARGPPARA
SCHEMBL28727713 0.79 LTA4H (0.46) CALM1SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL28616587 0.78 CALM1 (0.48) CALM1IDH1SLC6A2SLC6A4SLC6A3
SCHEMBL9503931 0.77 CALM1 (0.57) CALM1PPARGPPARAIDH1PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed