Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624229 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL20140704 | 0.76 | TDP1 (0.39) | CYP1A2ALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL25604912 | 0.73 | ALDH1A1 (0.43) | ERN1ALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL25624226 | 0.72 | CYP1A2 (0.52) | CYP1A2ALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL20636582 | 0.71 | ALDH1A1 (0.38) | CYP1A2ERN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29956228 | 0.70 | CTSB (0.49) | ALDH1A1CYP3A4MAPTHSD17B10KDM4E | |
| SCHEMBL29956553 | 0.69 | SMN1; SMN2 (0.51) | CYP1A2ALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL203719 | 0.69 | ERN1 (0.47) | CYP1A2ERN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL17533490 | 0.69 | ALDH1A1 (0.53) | CYP1A2ERN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL7826900 | 0.67 | ALDH1A1 (0.59) | CYP1A2ERN1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227290-B1 | 2H-PYRAZOLO[4,3-B]PYRIDINES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-11-21 | — | — | EP | disclosed |
| US-20180282319-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | US | disclosed |
| EP-3227290-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087422-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282319-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | CYP1A2 260/4885ERN1 1858/4885ALDH1A1 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.