Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924582 | 0.83 | THRB (0.39) | ALDH1A1KDM4EHTTTSHRMAPT | |
| SCHEMBL13116411 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTTMAPTFSCN1 | |
| SCHEMBL2928786 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HTTTSHRMAPTLMNA | |
| SCHEMBL13116342 | 0.74 | CA2 (0.35) | ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL28103068 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HTTHPGD | |
| SCHEMBL12158705 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21676872 | 0.73 | ERN1 (0.46) | ALDH1A1KDM4EMAPTFSCN1KMT2A | |
| SCHEMBL11660278 | 0.72 | ALDH1A1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL13116439 | 0.72 | LMNA (0.47) | ALDH1A1KDM4EHTTTSHRLMNA | |
| SCHEMBL10277747 | 0.72 | MAPT (0.33) | ALDH1A1KDM4EHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46024-E1 | Thyroid hormone analogs | HOFFMANN-LA ROCHE INC. (US) | 2016-06-07 | — | — | US | disclosed |