Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228188 | 0.83 | PTGS2 (0.40) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2895850 | 0.83 | ABL1 (0.47) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL26689624 | 0.79 | ALDH1A1 (0.57) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL5629366 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL6824936 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL21711898 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL18829858 | 0.76 | CA12 (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31615975 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL17804340 | 0.75 | TSHR (0.40) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3575890 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |