Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133579 | 0.80 | ALDH1A1 (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL24177617 | 0.77 | ALDH1A1 (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL2302761 | 0.77 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4298953 | 0.77 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20094 | 0.77 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17197994 | 0.77 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13583289 | 0.74 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Etoglucid SCHEMBL8442 | 0.74 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1005362 | 0.74 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8621977 | 0.74 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697889-B2 | Metal compound, polymerizable composition containing the same, resin, method for producing the resin, and use of the resin | MITSUI CHEMICALS, INC. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-8637633-B2 | Polymerizable composition, and resin and optical part using the same | MITSUI CHEMICALS, INC. (JP) | 2014-01-28 | — | — | US | disclosed |
| EP-2253626-B1 | THIETANE COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, RESIN, METHOD FOR PRODUCING THE RESIN, AND USE OF THE POLYMERIZABLE COMPOSITION AND THE RESIN | MITSUI CHEMICALS INC (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-8426551-B2 | Metal thietane compound, polymerizable composition containing the compound, resin and use of the resin | MITSUI CHEMICALS, INC. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8420718-B2 | Composition, polymerizable composition, resin, optical component, and method for producing the composition | MITSUI CHEMICALS, INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8394891-B2 | Additive for polymerizable composition, polymerizable composition containing the same and use of the polymerizable composition | MITSUI CHEMICALS, INC. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8362280-B2 | Thietane compound, polymerizable composition containing the same, resin, method for producing the resin, and use of the polymerizable composition and the resin | MITSUI CHEMICALS, INC. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20130018169-A1 | Metal Thietane Compound, Polymerizable Composition Containing the Compound, Resin and Use of the Resin | MITSUI CHEMICALS, INC. (JP) | 2013-01-17 | — | — | US | disclosed |
| US-8349996-B2 | Compound, polymerizable composition, resin, and use of the composition and the resin | MITSUI CHEMICALS, INC. (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20130005934-A1 | Polymerizable Composition, and Resin and Optical Part Using the Same | MITSUI CHEMICALS, INC (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20100298519-A1 | POLYMERIZABLE COMPOSITION, AND RESIN AND OPTICAL PART USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-2253626-A1 | THIETANE COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, RESIN, METHOD FOR PRODUCING THE RESIN, AND USE OF THE RESIN | Mitsui Chemicals, Inc. (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-20100286334-A1 | ADDITIVE FOR POLYMERIZABLE COMPOSITION, POLYMERIZABLE COMPOSITION CONTAINING THE SAME AND USE OF THE POLYMERIZABLE COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100240862-A1 | METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND, RESIN AND USE OF THE RESIN | MITSUI CHEMICALS, INC. (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-1482002-B1 | POLYMERIZABLE COMPOSITION CONTAINING NOVEL CYCLIC SULFUR COMPOUND AND RESIN OBTAINED BY CURING THE POLYMERIZABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2010-04-28 | — | — | EP | disclosed |
| US-20100063246-A1 | POLYMERIZABLE COMPOSITION, RESIN USING THE SAME, OPTICAL COMPONENT AND LENS | MITSUI CHEMICALS, INC. (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-2014700-A1 | POLYMERIZABLE COMPOSITION, RESIN USING THE SAME AND OPTICAL COMPONENT | Mitsui Chemicals, Inc. (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-7132501-B2 | Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition | MITSUI CHEMICALS, INC. (JP) | 2006-11-07 | — | — | US | disclosed |
| US-20050215757-A1 | Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition | MITSUI CHEMICALS, INC. (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1482002-A1 | POLYMERIZABLE COMPOSITION CONTAINING NOVEL CYCLIC SULFUR COMPOUND AND RESIN OBTAINED BY CURING THE POLYMERIZABLE COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018169-A1 | Metal Thietane Compound, Polymerizable Composition Containing the Compound, Resin and Use of the Resin | TERB1, TPR, TMSB10 | TSHR 1656/4885SMN1; SMN2 2377/4885ALDH1A1 3284/4885 |
| US-20100240862-A1 | METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND, RESIN AND USE OF THE RESIN | TERB1, TPR, TBXAS1 | TSHR 1828/4885SMN1; SMN2 903/4885ALDH1A1 3357/4885 |
| US-20100286334-A1 | ADDITIVE FOR POLYMERIZABLE COMPOSITION, POLYMERIZABLE COMPOSITION CONTAINING THE SAME AND USE OF THE POLYMERIZABLE COMPOSITION | B2M, MSH2, PBRM1 | TSHR 4777/4885SMN1; SMN2 105/4885ALDH1A1 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.