SCHEMBL17808016

SCHEMBL17808016

c1ccc(-c2nc(-c3ccc(-c4cc5ccccc5c5ccccc45)cc3)cc(-c3cccc(-c4cccnc4)c3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.62
CYP11B2 P19099 3/20 0.47
CYP19A1 P11511 2/20 0.47
CYP17A1 P05093 1/20 0.47
DHODH Q02127 1/20 0.46
KMO O15229 1/20 0.44
GPR84 Q9NQS5 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 4/20 0.43
KDM4E B2RXH2 4/20 0.43
GLA P06280 3/20 0.43
LMNA P02545 2/20 0.43
CYP2C9 P11712 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17808141 0.99 CYP11B1 (0.60) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL17918139 0.98 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL24252581 0.96 CYP11B1 (0.63) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL17918144 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL30296744 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL24252590 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL17918039 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL21945083 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL17808077 0.95 CYP11B1 (0.62) CYP11B1CYP11B2CYP19A1CYP17A1DHODH
SCHEMBL17808039 0.95 CYP11B1 (0.65) CYP11B1CYP11B2CYP19A1CYP17A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309235-B1 ORGANIC LIGHT EMITTING ELEMENT HAVING HIGH EFFICIENCY SFC CO LTD (KR) 2023-10-18 EP disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
EP-3156402-B1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-11-10 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-10950802-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2021-03-16 US disclosed
US-20200365813-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2020-11-19 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
EP-3244463-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-07-22 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3229284-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-10-11 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885CYP11B2 470/4885CYP19A1 42/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885CYP11B2 2329/4885CYP19A1 1535/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885CYP11B2 2329/4885CYP19A1 1535/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 CYP11B1 1190/4885CYP11B2 880/4885CYP19A1 1008/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B1 1637/4885CYP11B2 1456/4885CYP19A1 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.