SCHEMBL17808044

SCHEMBL17808044

c1cncc(-c2cccc(-c3cc(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)nc(-c4cccc5ccccc45)n3)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.59
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 2/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP11B2 P19099 4/20 0.45
CYP19A1 P11511 2/20 0.45
CYP17A1 P05093 1/20 0.45
DHODH Q02127 1/20 0.42
TNF P01375 1/20 0.41
GPR84 Q9NQS5 1/20 0.40
KMO O15229 1/20 0.39
CYP2C9 P11712 1/20 0.38
PDK2 Q15119 1/20 0.38
PIK3CA P42336 1/20 0.38
BCHE P06276 1/20 0.37
PGR P06401 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17918130 0.95 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17918027 0.95 CYP11B1 (0.62) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17808043 0.94 CYP11B1 (0.63) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL22461621 0.93 CYP11B1 (0.58) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL19167092 0.91 CYP11B1 (0.54) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL23095081 0.91 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17918050 0.91 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL30296882 0.91 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17918048 0.91 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL30296900 0.91 CYP11B1 (0.56) CYP11B1KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309235-B1 ORGANIC LIGHT EMITTING ELEMENT HAVING HIGH EFFICIENCY SFC CO LTD (KR) 2023-10-18 EP disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-10950802-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2021-03-16 US disclosed
EP-3754739-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2020-12-23 EP disclosed
US-20200365813-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2020-11-19 US disclosed
EP-3244463-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-07-22 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-20190273216-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-05 US disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885KDM4E 1822/4885ALDH1A1 228/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885KDM4E 1255/4885ALDH1A1 329/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 CYP11B1 1190/4885KDM4E 2113/4885ALDH1A1 357/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B1 1637/4885KDM4E 1478/4885ALDH1A1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.