SCHEMBL17808641

SCHEMBL17808641

Cc1cccc(C(c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5ccc(N(c6ccccc6)c6ccc(-c7ccc(N(c8cccc(C)c8)c8cccc(C)c8)cc7)cc6)cc5)cc4)cc3)cc2)c2cccc(C)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.40
MAPT P10636 5/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ACP3 P15309 1/20 0.38
TP53 P04637 2/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10259894 1.00 EPHX1 (0.40) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL2609918 1.00 EPHX1 (0.40) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL14285388 1.00 EPHX1 (0.40) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL16625482 0.97 EPHX1 (0.39) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL17016477 0.97 EPHX1 (0.39) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL10092973 0.97 EPHX1 (0.39) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL22793737 0.97 SLC6A2 (0.40) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL22251502 0.97 EPHX1 (0.42) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL12914386 0.95 HSD17B1 (0.39) EPHX1MAPTSLC6A2SLC6A4ACP3
SCHEMBL10001260 0.95 MAPT (0.42) EPHX1MAPTSLC6A2SLC6A4ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10461261-B2 Compound, light emitting material, and organic light emitting device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-10-29 US disclosed
US-10256415-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-04-09 US disclosed
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2017-04-20 US disclosed
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2017-04-20 US disclosed
US-20160164000-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-09 US disclosed
US-20160164000-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160164000-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DRD1, DRD2, AAAS EPHX1 569/4885MAPT 582/4885SLC6A2 2395/4885
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND H1-0, CRY1, CRY2 EPHX1 2871/4885MAPT 1962/4885SLC6A2 2982/4885
US-10256415-B2 Light-emitting material, organic light-emitting device, and compound H1-0, CRY1, CRY2 EPHX1 2871/4885MAPT 1962/4885SLC6A2 2982/4885
US-10461261-B2 Compound, light emitting material, and organic light emitting device DRD1, DRD2, AAAS EPHX1 569/4885MAPT 582/4885SLC6A2 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.