Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | ESR1 | P03372 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013340 | 0.88 | LMNA (0.78) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL10079788 | 0.87 | LMNA (0.77) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL13015302 | 0.87 | LMNA (0.77) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL17817390 | 0.87 | LMNA (0.56) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL16393333 | 0.85 | LMNA (0.59) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL2610024 | 0.85 | LMNA (0.59) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL17808702 | 0.85 | ESR1 (0.58) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL10013350 | 0.83 | ESR1 (0.71) | LMNAHSD17B10ESR1SMN1; SMN2ADORA3 | |
| SCHEMBL14924236 | 0.81 | ESR1 (0.77) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL5265450 | 0.81 | ESR1 (0.77) | LMNAHSD17B10ESR1SMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170370950-A1 | BIOTIN CONJUGATES OF ANALYTES CONTAINING AMINO, HYDROXYL, OR THIOL FUNCTIONAL GROUPS FOR USE IN IMMUNODIAGNOSTIC ASSAYS | Calbiotech, Inc. | 2017-12-28 | — | — | US | disclosed |
| US-20160161473-A1 | BIOTIN CONJUGATES OF ANALYTES CONTAINING AMINO, HYDROXYL, OR THIOL FUNCTIONAL GROUPS FOR USE IN IMMUNODIAGNOSTIC ASSAYS | Calbiotech, Inc. | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170370950-A1 | BIOTIN CONJUGATES OF ANALYTES CONTAINING AMINO, HYDROXYL, OR THIOL FUNCTIONAL GROUPS FOR USE IN IMMUNODIAGNOSTIC ASSAYS | SHBG, BTD, CYP24A1 | LMNA 2724/4885HSD17B10 584/4885ESR1 52/4885 |
| US-20160161473-A1 | BIOTIN CONJUGATES OF ANALYTES CONTAINING AMINO, HYDROXYL, OR THIOL FUNCTIONAL GROUPS FOR USE IN IMMUNODIAGNOSTIC ASSAYS | SHBG, BTD, CYP24A1 | LMNA 2482/4885HSD17B10 675/4885ESR1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.