Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 4/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 2/20 | 0.46 |
| ▸ | GART | P22102 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15071549 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL18118150 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL14883270 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL17789093 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL14946101 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL15044550 | 1.00 | UMPS (0.52) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL15745776 | 0.87 | UMPS (0.47) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL15249855 | 0.82 | UMPS (0.51) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL15277191 | 0.80 | UMPS (0.48) | UMPSDNPH1ATICGARTFBP1 | |
| SCHEMBL15257897 | 0.80 | UMPS (0.48) | UMPSDNPH1ATICGARTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170252461-A1 | HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA | MODERNATX, INC. | 2017-09-07 | — | — | US | disclosed |
| US-9572897-B2 | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins | MODERNATX, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160158385-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS | ARES CAPITAL CORPORATION, AS AGENT | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158385-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS | POLRMT, POLN, PHAX | UMPS 1052/4885DNPH1 3443/4885ATIC 1192/4885 |
| US-20170252461-A1 | HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA | RNGTT, NSUN3, CPSF6 | UMPS 329/4885DNPH1 1742/4885ATIC 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.