Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30226846 | 0.86 | HSD17B10 (0.41) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL1041519 | 0.86 | HSD17B10 (0.41) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL13837650 | 0.85 | HSD17B10 (0.42) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL10070164 | 0.79 | KDM4E (0.41) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL27414872 | 0.79 | ALDH1A1 (0.44) | HSD17B10KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL7764568 | 0.77 | CNR1 (0.39) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL1506777 | 0.75 | MAPT (0.45) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL5036714 | 0.74 | GABRA1 (0.42) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8974252 | 0.74 | KDM4E (0.50) | HSD17B10KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL2487112 | 0.73 | HSD17B10 (0.50) | HSD17B10KDM4EMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089565-A1 | MIXED PHOSPHORUS ESTERS FOR LUBRICANT APPLICATIONS | THE LUBRIZOL CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |