SCHEMBL178146

SCHEMBL178146

CCC(S)c1cccnc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CFTR P13569 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
GOPC Q9HD26 1/20 0.48
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
KDM4E B2RXH2 1/20 0.43
CYP19A1 P11511 1/20 0.43
KCNA5 P22460 2/20 0.42
CYP17A1 P05093 1/20 0.42
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178165 0.85 CFTR (0.46) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL27924216 0.84 SMN1; SMN2 (0.50) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL1579049 0.80 LMNA (0.57) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL21009583 0.80 LMNA (0.57) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL7952831 0.80 LMNA (0.57) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL32346286 0.80 LMNA (0.57) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL12154822 0.79 CFTR (0.52) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL658876 0.79 CFTR (0.57) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
Hydrochloric Acid SCHEMBL5448253 0.78 LMNA (0.55) SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2
SCHEMBL27943512 0.78 LMNA (0.43) SMN1; SMN2LMNAL3MBTL1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390243-B1 PROCESS FOR PREPARING BISPHENOL MITSUBISHI CHEM CORP (JP) 2020-07-08 EP disclosed
US-8445731-B2 Process for producing bisphenol compound MITSUBISHI CHEMICAL CORPORATION (JP) 2013-05-21 US disclosed
US-20120010434-A1 PROCESS FOR PRODUCING BISPHENOL COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2012-01-12 US disclosed
EP-2390243-A1 PROCESS FOR PREPARING BISPHENOL Mitsubishi Chemical Corporation (JP) 2011-11-30 EP disclosed
US-20110256982-A1 INTERLOCK CIRCUIT FOR UTILITY VEHICLE PARK BRAKE DEERE & COMPANY 2011-10-20 US disclosed
EP-0165753-B1 HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-11 EP disclosed
US-4784684-A Herbicidal pyridinesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-15 US disclosed
US-4668279-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-26 US disclosed
EP-0165753-A2 Herbicidal thiophenesulfonamides and pyridinesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010434-A1 PROCESS FOR PRODUCING BISPHENOL COMPOUND SULT2A1, SULT1A1, PLPBP SMN1; SMN2 3867/4885LMNA 4145/4885L3MBTL1 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.