Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783661 | 0.73 | BACE1 (0.34) | — | |
| SCHEMBL2419495 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1NPSR1MEN1 | |
| SCHEMBL7929775 | 0.63 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1NPSR1MEN1 | |
| SCHEMBL7930788 | 0.63 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1NPSR1MEN1 | |
| SCHEMBL11139017 | 0.63 | L3MBTL1 (0.56) | ALDH1A1MAPTL3MBTL1NPSR1MEN1 | |
| SCHEMBL3411326 | 0.63 | MAPT (0.42) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL620629 | 0.62 | MCHR1 (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5155766 | 0.62 | ALDH1A1 (0.43) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL11905880 | 0.61 | GRM5 (0.49) | ALDH1A1MAPTL3MBTL1NPSR1MEN1 | |
| SCHEMBL1002382 | 0.61 | LTA4H (0.59) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| WO-2010072310-A1 | 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-2196461-A1 | 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | P2RX5, SLC1A5, P2RX4 | ALDH1A1 2671/4885MAPT 3255/4885L3MBTL1 1505/4885 |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | P2RX5, P2RX4, SLC1A5 | ALDH1A1 2519/4885MAPT 3327/4885L3MBTL1 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.