Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147045 | 0.80 | PIK3CD (0.40) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL14616910 | 0.78 | SSTR4 (0.46) | CYP3A4SSTR4ALDH1A1TSHRTDP1 | |
| SCHEMBL25038132 | 0.78 | ALDH1A1 (0.35) | CYP3A4SSTR4ALDH1A1TSHRTDP1 | |
| SCHEMBL25004053 | 0.76 | KDM4E (0.43) | MAPTCYP3A4MAPK1ALDH1A1TSHR | |
| SCHEMBL26054973 | 0.74 | CAPN1 (0.34) | SSTR4ALDH1A1TSHRTDP1KIF11 | |
| SCHEMBL25003240 | 0.74 | CHEK1 (0.37) | MAPTLMNACYP3A4MAPK1ALDH1A1 | |
| SCHEMBL25003399 | 0.73 | ALDH1A1 (0.50) | MAPTMAPK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL23478904 | 0.73 | MAOA (0.45) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL25003207 | 0.73 | CYP1A2 (0.38) | MAPTLMNACYP3A4MAPK1ALDH1A1 | |
| SCHEMBL30166157 | 0.72 | PLAU (0.47) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160158200-A1 | Combinations of Hepatitis C Virus Inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158200-A1 | Combinations of Hepatitis C Virus Inhibitors | HAVCR2, EIF2AK2, MAVS | PDE4A 2968/4885PDE4B 3271/4885PDE4C 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.