SCHEMBL3147045

SCHEMBL3147045

FC(F)(F)c1cnc(Cl)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.40
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
APEX1 P27695 1/20 0.39
MAPK1 P28482 1/20 0.39
PMP22 Q01453 1/20 0.39
ULK1 O75385 1/20 0.39
BACE1 P56817 1/20 0.37
RPS6KA5 O75582 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
TNF P01375 1/20 0.35
CXCL8 P10145 1/20 0.35
PAX8 Q06710 1/20 0.35
KLF5 Q13887 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816446 0.80 PDE4A (0.39) PDE4APDE4BPDE4CPDE4DLMNA
SCHEMBL1536471 0.77 LMNA (0.49) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL14924258 0.77 PIK3CD (0.39) PIK3CDLMNAMAPTKMT2AMEN1
SCHEMBL12337987 0.76 SSTR4 (0.42) CYP3A4MAPK1ULK1BACE1KMT2A
SCHEMBL31696363 0.74 LMNA (0.54) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL3146937 0.73 CYP11B2 (0.43) ULK1BACE1KMT2AMEN1KIF11
SCHEMBL13728229 0.73 DYRK1A (0.40) LMNAKMT2AMEN1POLBHPGD
SCHEMBL20593890 0.72 PDE4A (0.43) PDE4APDE4BPDE4CPDE4DLMNA
SCHEMBL3141268 0.72 PDE4A (0.43) PDE4APDE4BPDE4CPDE4DLMNA
SCHEMBL196720 0.72 ALDH1A1 (0.55) PDE4APDE4BPDE4CPDE4DLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348711-B1 LUMINESCENT ELEMENT AND DISPLAY CANON KK (JP) 2018-06-13 EP disclosed
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
EP-1881050-B1 Luminescence device and display apparatus CANON KK (JP) 2013-01-09 EP disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-23 US disclosed
US-7544426-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2009-06-09 US disclosed
US-7527879-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
CN-100375749-C Luminescence device and display apparatus CANON KK (JP) 2008-03-19 CN disclosed
EP-1881050-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-01-23 EP disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 US disclosed
US-20070212570-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2007-09-13 US disclosed
US-7147935-B2 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2006-12-12 US disclosed
CN-1285601-C Light emitting device and display CANON KK (JP) 2006-11-22 CN disclosed
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2006-08-10 US disclosed
CN-1781925-A Luminescence device and display apparatus CANON KK (JP) 2006-06-07 CN disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency AP3M1, MLEC, MLX PIK3CD 2480/4885PDE4A 3881/4885PDE4B 3858/4885
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS SOD1, NLRP1, LUC7L2 PIK3CD 2822/4885PDE4A 3932/4885PDE4B 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.