Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923017 | 0.98 | PDK2 (0.47) | PDK2NPSR1OPRM1OPRD1CHRNA1 | |
| SCHEMBL12619958 | 0.89 | CHRNA1 (0.40) | PDK2NPSR1OPRM1OPRD1CHRNA1 | |
| SCHEMBL19027860 | 0.89 | CHRNA1 (0.40) | PDK2NPSR1OPRM1OPRD1CHRNA1 | |
| SCHEMBL23996970 | 0.85 | PDK2 (0.45) | PDK2THRBTDP1HSP90AA1 | |
| SCHEMBL824239 | 0.81 | PDK2 (0.57) | PDK2OPRM1OPRD1THRBTDP1 | |
| SCHEMBL28607030 | 0.80 | PDK2 (0.49) | PDK2OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL1495151 | 0.79 | ESR1 (0.47) | PDK2NPSR1OPRM1OPRD1CHRNA1 | |
| SCHEMBL17816648 | 0.79 | PDK2 (0.46) | PDK2NPSR1OPRM1OPRD1THRB | |
| SCHEMBL30153131 | 0.79 | ESR1 (0.47) | PDK2NPSR1OPRM1OPRD1CHRNA1 | |
| SCHEMBL17816650 | 0.79 | PDK2 (0.49) | PDK2NPSR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-10573818-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | AR, ARL1, ESR2 | PDK2 3312/4885NPSR1 2568/4885OPRM1 396/4885 |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, EFNA1 | PDK2 893/4885NPSR1 2026/4885OPRM1 246/4885 |
| US-10573818-B2 | Materials for organic electroluminescent devices | PIEZO1, LEF1, EFNA1 | PDK2 893/4885NPSR1 2026/4885OPRM1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.