Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15213862 | 1.00 | KDM4E (0.36) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL24546538 | 1.00 | KDM4E (0.36) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL15892450 | 0.99 | KDM4E (0.35) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL15892457 | 0.99 | KDM4E (0.35) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL24904790 | 0.99 | KDM4E (0.35) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL14681598 | 0.99 | KDM4E (0.35) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL30100129 | 0.96 | TSPO (0.37) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL14681531 | 0.96 | TSPO (0.37) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL17816735 | 0.96 | TSPO (0.37) | KDM4EATML3MBTL1TSPOKMT2A | |
| SCHEMBL15892485 | 0.95 | TSPO (0.35) | KDM4EATML3MBTL1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-10573818-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| US-10431751-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-01 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170213970-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
| US-20170213970-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10431751-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | KDM4E 901/4885ATM 1462/4885L3MBTL1 672/4885 |
| US-20170213970-A1 | Novel compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | KDM4E 965/4885ATM 1235/4885L3MBTL1 734/4885 |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, EFNA1 | KDM4E 2668/4885ATM 3782/4885L3MBTL1 2767/4885 |
| US-10573818-B2 | Materials for organic electroluminescent devices | PIEZO1, LEF1, EFNA1 | KDM4E 2668/4885ATM 3782/4885L3MBTL1 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.