SCHEMBL1781735

SCHEMBL1781735

C=C(C)C(=O)OCO[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 3/20 0.35
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
THRB P10828 2/20 0.33
PAX8 Q06710 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.33
GPR174 Q9BXC1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230456 0.93 ELANE (0.38) ELANEPOLBAPEX1HTTTDP1
SCHEMBL230780 0.84 TDP1 (0.49) ELANEPOLBAPEX1HTTTDP1
SCHEMBL2584263 0.80 ELANE (0.47) ELANEPOLBAPEX1HTTTDP1
SCHEMBL1642945 0.79 TDP1 (0.51) ELANEPOLBAPEX1HTTTDP1
SCHEMBL230468 0.78 ELANE (0.43) ELANEPOLBAPEX1HTTTDP1
SCHEMBL1780823 0.78 TDP1 (0.46) ELANEPOLBAPEX1HTTTDP1
SCHEMBL231730 0.77 ELANE (0.42) ELANEPOLBAPEX1HTTTDP1
SCHEMBL230455 0.77 ELANE (0.42) ELANEPOLBAPEX1HTTTDP1
SCHEMBL1784170 0.77 THRB (0.54) HTTALDH1A1TSHRTHRBALOX15
SCHEMBL27849594 0.77 MAPT (0.41) ELANEPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247590-B2 Method for preventing polymerization of unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2012-08-21 US disclosed
US-20110118493-A1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2011-05-19 US disclosed