Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780823 | 0.93 | TDP1 (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1781735 | 0.84 | ELANE (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1404303 | 0.82 | TDP1 (0.68) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL230778 | 0.82 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8899641 | 0.82 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL229200 | 0.81 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL230550 | 0.81 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8899918 | 0.81 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11521481 | 0.80 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL4577427 | 0.79 | TDP1 (0.73) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247590-B2 | Method for preventing polymerization of unsaturated organosilicon compounds | WACKER CHEMIE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20120004437-A1 | METHOD FOR PRODUCING (METH)ACRYLOSILANES | WACKER CHEMIE AG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20110118493-A1 | METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2011-05-19 | — | — | US | disclosed |