SCHEMBL230455

SCHEMBL230455

C=C(C)C(=O)OC[Si](C)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 3/20 0.36
THRB P10828 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
PAX8 Q06710 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.33
GPR174 Q9BXC1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231730 0.88 ELANE (0.42) ELANEPOLBAPEX1HTTTDP1
SCHEMBL230468 0.86 ELANE (0.43) ELANEPOLBAPEX1HTTTDP1
SCHEMBL230550 0.82 TDP1 (0.49) ELANEPOLBAPEX1HTTTDP1
SCHEMBL229250 0.78 THRB (0.54) ALDH1A1MAPTTSHRTHRBALOX15
SCHEMBL9337758 0.78 ELANE (0.41) ELANEPOLBAPEX1HTTTDP1
SCHEMBL840793 0.78 MAPT (0.46) ELANEPOLBAPEX1HTTTDP1
SCHEMBL1781735 0.77 ELANE (0.41) ELANEPOLBAPEX1HTTTDP1
SCHEMBL229200 0.77 TDP1 (0.49) ELANEPOLBAPEX1HTTTDP1
SCHEMBL8899918 0.77 TDP1 (0.49) ELANEPOLBAPEX1HTTTDP1
SCHEMBL2584263 0.75 ELANE (0.47) ELANEPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247590-B2 Method for preventing polymerization of unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2012-08-21 US disclosed
EP-2334690-B1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-07-25 EP disclosed
EP-2300486-B1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2012-03-28 EP disclosed
US-20120004437-A1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-01-05 US disclosed
US-20110118493-A1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2011-05-19 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 ELANE 1192/4885POLB 2487/4885APEX1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.