Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.98 |
| ▸ | GAA | P10253 | 6/20 | 0.98 |
| ▸ | GLA | P06280 | 5/20 | 0.98 |
| ▸ | TSHR | P16473 | 3/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.98 |
| ▸ | HPGD | P15428 | 3/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.98 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596179 | 0.84 | ALDH1A1 (0.71) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL18332920 | 0.79 | ALDH1A1 (0.72) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL27476154 | 0.76 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL19308467 | 0.75 | HTT (0.73) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL9395051 | 0.73 | CETP (0.77) | TSHRMAPK1MEN1KMT2AEP300 | |
| SCHEMBL5878480 | 0.73 | CETP (0.77) | TSHRMAPK1MEN1KMT2AEP300 | |
| SCHEMBL18248481 | 0.73 | CETP (0.63) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL27779139 | 0.72 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL31091435 | 0.72 | EP300 (0.66) | KDM4EALDH1A1GAAGLATSHR | |
| SCHEMBL17817448 | 0.71 | KDM4E (0.67) | KDM4EALDH1A1GAAGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | KDM4E 812/4885ALDH1A1 999/4885GAA 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.