Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.65 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781902 | 1.00 | GAPDH (0.65) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| SCHEMBL1783958 | 0.94 | GAPDH (0.56) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| SCHEMBL1783956 | 0.94 | GAPDH (0.56) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| SCHEMBL1781724 | 0.86 | TRPA1 (0.50) | GAPDHTRPA1MAPTDDAH1LMNA | |
| SCHEMBL1781723 | 0.86 | TRPA1 (0.50) | GAPDHTRPA1MAPTDDAH1LMNA | |
| SCHEMBL2746997 | 0.83 | GAPDH (0.67) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| SCHEMBL2746998 | 0.83 | GAPDH (0.67) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| SCHEMBL13317736 | 0.81 | GAPDH (0.58) | GAPDHTRPA1MAPTDDAH1TP53 | |
| SCHEMBL1786274 | 0.80 | SPHK1 (0.52) | GAPDHTRPA1MAPTDDAH1SPHK1 | |
| 4-Hydroxynon-2-Enal SCHEMBL3920 | 0.79 | GAPDH (1.00) | GAPDHTRPA1MAPTDDAH1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | GAPDH 3057/4885TRPA1 1/4885MAPT 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.