Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 6/20 | 0.45 |
| ▸ | GABRD | O14764 | 6/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.45 |
| ▸ | GABRE | P78334 | 6/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820038 | 0.81 | KDM1A (0.49) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17819790 | 0.79 | KDM1A (0.49) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17820661 | 0.78 | GABRP (0.49) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9189119 | 0.74 | KDM1A (0.61) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17819869 | 0.73 | GABRP (0.46) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29197451 | 0.71 | GABRP (0.55) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11661116 | 0.70 | ALDH1A1 (0.51) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6647679 | 0.70 | CA9 (0.49) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9180139 | 0.69 | MAPT (0.54) | KDM1AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28376670 | 0.69 | MGAM (0.69) | KDM1APTPN1CA9CA12IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-B1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | KDM1A 944/4885GABRP 4140/4885GABRD 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.