Biphenyl

Biphenyl

SCHEMBL1782043

Cc1cccc(C)c1C.O=P.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
TRPA1 O75762 2/20 0.44
AKR1B10 O60218 1/20 0.44
ABCB11 O95342 1/20 0.44
DHFR P00374 1/20 0.44
LMNA P02545 1/20 0.44
MPO P05164 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
AKR1B1 P15121 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4006535 0.92 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ATRPA1AKR1B10
SCHEMBL27629044 0.87 TRPA1 (0.52) ALDH1A1MEN1KMT2ATRPA1AKR1B10
O-Xylene SCHEMBL28088028 0.81 TSHR (0.67) ALDH1A1MEN1KMT2ATRPA1AKR1B10
Benzene SCHEMBL22829865 0.81 TRPA1 (0.58) ALDH1A1MEN1KMT2ATRPA1AKR1B10
SCHEMBL19431477 0.79 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ACYP3A4PTGS1
O-Xylene SCHEMBL1420011 0.79 TSHR (0.56) ALDH1A1MEN1KMT2ABRD4TSHR
Biphenyl SCHEMBL11408375 0.78 PDCD1 (0.55) ALDH1A1TRPA1KDM4ETSHRACHE
O-Xylene SCHEMBL3835918 0.78 TSHR (0.71) ALDH1A1MEN1KMT2ATRPA1AKR1B10
Biphenyl SCHEMBL27587661 0.78 ACHE (0.71) ALDH1A1LMNACYP1A2CYP3A4TDP1
Biphenyl SCHEMBL20493683 0.78 PDCD1 (0.46) ALDH1A1PTGS1PTGS2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8840986-B2 Laminate coated with radiation-hardenable printing ink or printing lacquer and moulded piece BAYER MATERIALSCIENCE AG (DE) 2014-09-23 US disclosed
US-20110117350-A1 LAMINATE COATED WITH RADIATION-HARDENABLE PRINTING INK OR PRINTING LACQUER AND MOULDED PIECE BAYER MATERIALSCIENCE AG 2011-05-19 US disclosed
US-7741635-B2 Composition for organic polymer gate insulating layer and organic thin film transistor using the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2010-06-22 US disclosed
EP-2073288-A2 Composition for organic polymer gate insulating layer and organic thin film transistor using the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2009-06-24 EP disclosed
US-20090152537-A1 COMPOSITION FOR ORGANIC POLYMER GATE INSULATING LAYER AND ORGANIC THIN FILM TRANSISTOR USING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2009-06-18 US disclosed