Biphenyl

Biphenyl

SCHEMBL4006535

Cc1cccc(C)c1C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
TSHR P16473 1/20 0.50
ACHE P22303 1/20 0.50
TRPA1 O75762 2/20 0.48
ATM Q13315 1/20 0.48
CYP1A2 P05177 2/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
AKR1B10 O60218 1/20 0.44
ABCB11 O95342 1/20 0.44
DHFR P00374 1/20 0.44
MPO P05164 1/20 0.44
CYP3A4 P08684 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
AKR1B1 P15121 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
AKR1C3 P42330 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1782043 0.92 ALDH1A1 (0.45) ALDH1A1TSHRACHETRPA1ATM
O-Xylene SCHEMBL28088028 0.88 TSHR (0.67) ALDH1A1TSHRACHETRPA1ATM
Benzene SCHEMBL22829865 0.87 TRPA1 (0.58) ALDH1A1TSHRACHETRPA1ATM
Biphenyl SCHEMBL11408375 0.85 PDCD1 (0.55) ALDH1A1TSHRACHETRPA1ATM
O-Xylene SCHEMBL3835918 0.84 TSHR (0.71) ALDH1A1TSHRACHETRPA1ATM
Biphenyl SCHEMBL27587661 0.84 ACHE (0.71) ALDH1A1TSHRACHECYP1A2LMNA
SCHEMBL40704 0.84
SCHEMBL5494561 0.84 TRPA1 (0.61) ALDH1A1TSHRACHETRPA1ATM
Biphenyl SCHEMBL6930550 0.83 CYP3A4 (0.56) ALDH1A1TSHRACHETRPA1ATM
SCHEMBL9792867 0.83 PDCD1 (0.53) ALDH1A1TSHRACHETRPA1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2073288-A2 Composition for organic polymer gate insulating layer and organic thin film transistor using the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2009-06-24 EP disclosed