SCHEMBL17822178

SCHEMBL17822178

CC(C)CC(NC(=O)c1ccccc1)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.65
CTSL P07711 4/20 0.63
CTSB P07858 2/20 0.63
CTSK P43235 2/20 0.63
CTSS P25774 1/20 0.63
CA1 P00915 2/20 0.57
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
CA2 P00918 2/20 0.56
F3 P13726 1/20 0.55
PDE4A P27815 3/20 0.54
PDE4B Q07343 2/20 0.54
PDE4C Q08493 2/20 0.54
PDE4D Q08499 2/20 0.54
PADI1 Q9ULC6 2/20 0.54
PADI4 Q9UM07 2/20 0.54
PADI2 Q9Y2J8 2/20 0.54
PADI6 Q6TGC4 1/20 0.54
PADI3 Q9ULW8 1/20 0.54
MAPK14 Q16539 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4194914 1.00 HPGDS (0.65) HPGDSCTSLCTSBCTSKCTSS
SCHEMBL20277660 0.89 CTSL (0.65) HPGDSCTSLCTSBCTSKCTSS
SCHEMBL2158906 0.87 CTSL (0.67) CTSLCTSBCTSKCTSSCA1
SCHEMBL2158900 0.87 CTSL (0.67) CTSLCTSBCTSKCTSSCA1
SCHEMBL4465251 0.87 CTSL (0.67) CTSLCTSBCTSKCTSSCA1
SCHEMBL7432512 0.84 CTSL (0.63) CTSLCTSBCTSKCTSSCA1
SCHEMBL10784866 0.83 CTSL (0.70) CTSLCTSBCTSKCTSSCA2
SCHEMBL23470237 0.83 CTSL (0.70) CTSLCTSBCTSKCTSSF3
SCHEMBL10407750 0.83 TAS1R3 (0.68) CTSLCTSBCTSKCTSS
SCHEMBL6241209 0.83 TAS1R3 (0.68) CTSLCTSBCTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 US disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 US disclosed
US-20180255813-A1 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2018-09-13 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
EP-3229606-A2 METHODS FOR MODULATING TASTE RECEPTORS Mars, Incorporated (US) 2017-10-18 EP disclosed
EP-3229612-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2017-10-18 EP disclosed
EP-3229610-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2017-10-18 EP disclosed
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094702-A2 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094682-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094682-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed