SCHEMBL1782289

SCHEMBL1782289

CCCCCC(C)(O)/C=C/C(C)=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FDPS P14324 9/20 0.38
GGPS1 O95749 6/20 0.38
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
MBOAT4 Q96T53 1/20 0.36
CES2 O00748 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782290 1.00 MEN1 (0.40) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL1784840 0.94 ATM (0.34) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL1784843 0.94 ATM (0.34) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL1783089 0.86 ALOX15 (0.32) FDPS
SCHEMBL1783086 0.86 ALOX15 (0.32) FDPS
SCHEMBL15333382 0.79 FDPS (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL15333380 0.79 FDPS (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL8153612 0.78 FDPS (0.38) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL11178597 0.78 FDPS (0.38) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL1784216 0.77 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 MEN1 251/4885MAPT 906/4885KMT2A 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.