Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047820 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL7108921 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL18679956 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL13556930 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL19728168 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8123878 | 0.75 | CA1 (0.60) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL10781788 | 0.75 | CA1 (0.51) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27508854 | 0.74 | CA1 (0.58) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL1081854 | 0.74 | CA2 (0.53) | ALDH1A1HCAR2TDP1KMT2ACA9 | |
| SCHEMBL347596 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118473-A1 | PROCESS FOR CONVERTING 9-DIHYDRO-13ACETYLBACCATIN III PACLITAXEL AND DOCETAXEL | 6570763 CANADA INC. (CA) | 2011-05-19 | — | — | US | claimed |
| EP-2183234-A1 | PROCESS FOR CONVERTING 9-DIHYDRO-13-ACETYLBACCATIN III INTO DOCETAXEL OR PACLITAXEL | 6570763 Canada Inc. (CA) | 2010-05-12 | — | — | EP | claimed |
| WO-2009023967-A1 | PROCESS FOR CONVERTING 9-DIHYDRO-13-ACETYLBACCATIN III INTO DOCETAXEL OR PACLITAXEL | 6570763 CANADA INC. (CA) | 2009-02-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118473-A1 | PROCESS FOR CONVERTING 9-DIHYDRO-13ACETYLBACCATIN III PACLITAXEL AND DOCETAXEL | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TUBB6, TUBB3 | ALDH1A1 813/4885HCAR2 2655/4885TDP1 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.