Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 5/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330575 | 0.98 | HSP90AA1 (0.44) | HSP90AA1PDPK1RAB9AADORA2AADORA1 | |
| SCHEMBL28550298 | 0.78 | ADORA2A (0.37) | HSP90AA1PDPK1RAB9AADORA2AADORA1 | |
| SCHEMBL5463009 | 0.77 | PDPK1 (0.33) | HSP90AA1PDPK1RAB9AADORA2AADORA1 | |
| SCHEMBL30511083 | 0.72 | — | — | |
| SCHEMBL18210540 | 0.71 | HSP90AA1 (0.49) | HSP90AA1PDPK1RAB9AADORA2AADORA1 | |
| SCHEMBL1673128 | 0.69 | — | — | |
| SCHEMBL102331 | 0.69 | PDPK1 (0.59) | HSP90AA1PDPK1RAB9AADORA2AADORA1 | |
| SCHEMBL4902877 | 0.68 | RAB9A (0.61) | HSP90AA1PDPK1RAB9ALOXL2CYP2A6 | |
| Aminothiazole SCHEMBL9354394 | 0.68 | ALDH1A1 (0.54) | HSP90AA1RAB9A | |
| SCHEMBL1389231 | 0.68 | HSP90AA1 (0.42) | HSP90AA1PDPK1RAB9AADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134140-A1 | ORALLY ADMINISTERED COMPOSITION FOR TREATING CYSTIC FIBROSIS, COPD, ASTHMA AND OTHER INFLAMMATORY CONDITIONS | BURCH LAURANELL HARRISON (US) | 2019-05-09 | — | — | US | claimed |
| EP-1819721-A1 | MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | Plant Bioscience Limited (GB) | 2007-08-22 | — | — | EP | claimed |
| WO-2006054102-A1 | MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | PLANT BIOSCIENCE LIMITED (GB) | 2006-05-26 | — | — | WO | claimed |
| CN-114867724-B | Process for preparing thiazolyl pyrazole carboxylic acid and intermediates thereof | 班塔姆制药有限责任公司 | 2025-11-07 | — | — | CN | disclosed |
| US-20250326778-A1 | PYRAZOLE COMPOUNDS AND METHOD FOR MAKING AND USING THE COMPOUNDS | RIGEL PHARMACEUTICALS, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| EP-3976605-B1 | METHODS FOR MAKING THIAZOLYLPYRAZOLE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR | BANTAM PHARMACEUTICAL LLC (US) | 2025-08-20 | — | — | EP | disclosed |
| US-12378234-B2 | Crystalline polymorphs of a 1-thiazol-2-yl-pyrazole-5-carboxylic acid derivative | BANTAM PHARMACEUTICAL, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| US-12378234-B2 | Crystalline polymorphs of a 1-thiazol-2-yl-pyrazole-5-carboxylic acid derivative | BANTAM PHARMACEUTICAL, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| US-12358905-B2 | Methods for making thiazolypyrazole carboxylic acids and intermediates therefor | Bantam Pharamceutical, LLC (US) | 2025-07-15 | — | — | US | disclosed |
| US-12358905-B2 | Methods for making thiazolypyrazole carboxylic acids and intermediates therefor | Bantam Pharamceutical, LLC (US) | 2025-07-15 | — | — | US | disclosed |
| EP-3799871-B1 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOTOTIC BAX | DANA FARBER CANCER INST INC (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2004045001-A2 | ORGANIC LIGHT EMITTING MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040091738-A1 | Organic light emitting materials and devices | UNIVERSAL DISPLAY CORPORATION | 2004-05-13 | — | — | US | disclosed |
| CN-1492874-A | Macrolide antibiotics | — | 2004-04-28 | — | — | CN | disclosed |
| US-20040077557-A1 | Macrolide antibiotics | GLAXO GROUP LIMITED (GB) | 2004-04-22 | — | — | US | disclosed |
| EP-1383747-A1 | FUSED PYRIMIDINES AS ANTAGONISTS OF THE CORTICOTROPIN RELEASING FACTOR (CRF) | GLAXO GROUP LIMITED (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2003008412-A2 | HETERO-BICYCLIC CRF ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |
| WO-2002088095-A1 | FUSED PYRIMIDINES AS ANTAGONISTS OF THE CORTICOTROPIN RELEASING FACTOR (CRF) | GLAXO GROUP LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326778-A1 | PYRAZOLE COMPOUNDS AND METHOD FOR MAKING AND USING THE COMPOUNDS | IRAK3, IRAK1, IRAK2 | HSP90AA1 4192/4885PDPK1 94/4885RAB9A 3229/4885 |
| US-12358905-B2 | Methods for making thiazolypyrazole carboxylic acids and intermediates therefor | ABAT, WEE1, HADHB | HSP90AA1 2675/4885PDPK1 573/4885RAB9A 3849/4885 |
| US-20040077557-A1 | Macrolide antibiotics | MALT1, MRPL21, IL1R1 | HSP90AA1 1034/4885PDPK1 4231/4885RAB9A 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.