Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isothiazole SCHEMBL27711363 | 0.87 | RAB9A (0.36) | HSP90AA1RAB9APDPK1SMPD3SPHK2 | |
| SCHEMBL28149989 | 0.78 | METAP1 (0.41) | HSP90AA1RAB9APDPK1CYP2A6METAP1 | |
| SCHEMBL87533 | 0.69 | — | — | |
| SCHEMBL102331 | 0.69 | PDPK1 (0.59) | HSP90AA1RAB9APDPK1SMPD3LOXL2 | |
| SCHEMBL1024793 | 0.69 | FBP1 (0.32) | — | |
| SCHEMBL1782526 | 0.68 | HSP90AA1 (0.46) | HSP90AA1RAB9APDPK1SMPD3SPHK2 | |
| SCHEMBL219657 | 0.68 | KDM4E (0.50) | RAB9ACYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL31556353 | 0.67 | PDPK1 (0.56) | HSP90AA1RAB9APDPK1SMPD3LOXL2 | |
| SCHEMBL30534095 | 0.67 | PDPK1 (0.56) | HSP90AA1RAB9APDPK1SMPD3LOXL2 | |
| SCHEMBL30632310 | 0.67 | PDPK1 (0.56) | HSP90AA1RAB9APDPK1SMPD3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394054-B1 | NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL SCIENT IND RES (IN) | 2019-11-06 | — | — | EP | claimed |
| EP-2968324-B1 | SUBSTITUTED PYRIDAZINONE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME (US) | 2018-04-18 | — | — | EP | claimed |
| US-9353104-B2 | Substituted pyridizinone derivatives as PDE10 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-05-31 | — | — | US | claimed |
| US-20160016947-A1 | SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-01-21 | — | — | US | claimed |
| EP-2968324-A1 | SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014150114-A1 | SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-09-25 | — | — | WO | claimed |
| WO-2014139150-A1 | SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-09-18 | — | — | WO | claimed |
| US-7968530-B2 | Organic derivatives, their salts and use for the control of phytopathogens | ISAGRO S.P.A (IT) | 2011-06-28 | — | — | US | claimed |
| US-20090029948-A1 | Organic Derivatives, Their Salts and Use for the Control of Phytopathogens | ISAGRO S.P.A. (IT) | 2009-01-29 | — | — | US | claimed |
| CN-101316509-A | Compounds and relative use for the control of phytopathogens | ISAGRO RICERCA SRL (IT) | 2008-12-03 | — | — | CN | claimed |
| EP-1976826-A2 | ORGANIC DERIVATIVES, THEIR SALTS AND USE FOR THE CONTROL OF PHYTOPATHOGENS | ISAGRO S.p.A. (IT) | 2008-10-08 | — | — | EP | claimed |
| WO-2007071428-A2 | ORAGANIC DERIVATIVES, THEIR SALTS AND USE FOR THE CONTROL OF PHYTO PATHOGENS | ISAGRO S.P.A. (IT) | 2007-06-28 | — | — | WO | claimed |
| EP-0625970-B1 | SULFONAMIDE HERBICIDES | AGREVO UK LTD (GB) | 1997-09-17 | — | — | EP | claimed |
| WO-2026105052-A1 | BIARYL ACID COMPOUNDS | PFIZER INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| WO-2026088071-A1 | SUBSTITUTED FUSED HETEROARYL LACTAM COMPOUNDS | PFIZER INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4658636-A1 | LIPID COMPOUNDS AND USES THEREOF | Pfizer Inc. (US) | 2025-12-10 | — | — | EP | disclosed |
| EP-0161841-A1 | 2-(N-substituteguanidino)-4-hetero-arylthiazole antiulcer agents | PFIZER INC. (US) | 1985-11-21 | — | — | EP | disclosed |
| US-4503064-A | BACTERICIDAL ANTIBIOTICS | SCHERING CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0021688-A1 | 7-(Thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |
| US-3767654-A | THIAZINE AND THIAZOLE TRIAZOLES | SQUIBB & SONS INC | 1973-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029948-A1 | Organic Derivatives, Their Salts and Use for the Control of Phytopathogens | ERG28, OAT, OSTC | HSP90AA1 2898/4885RAB9A 3649/4885PDPK1 2850/4885 |
| US-20160016947-A1 | SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS | PDE12, PDE5A, PDE10A | HSP90AA1 2673/4885RAB9A 447/4885PDPK1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.