Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834016 | 0.91 | RAB9A (0.48) | RAB9ANPC1LMNATSHRMAPK1 | |
| SCHEMBL17834018 | 0.88 | KMT2A (0.56) | RAB9ANPC1LMNATSHRMAPK1 | |
| SCHEMBL17834021 | 0.87 | KMT2A (0.58) | RAB9ANPC1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL17834027 | 0.87 | LMNA (0.53) | RAB9ANPC1LMNATSHRMAPK1 | |
| SCHEMBL17834026 | 0.87 | RAB9A (0.61) | RAB9ANPC1LMNAL3MBTL1KMT2A | |
| SCHEMBL17834017 | 0.86 | NPC1 (0.58) | RAB9ANPC1LMNATSHRL3MBTL1 | |
| SCHEMBL17834025 | 0.86 | CYP19A1 (0.44) | RAB9ANPC1LMNATSHRMAPK1 | |
| SCHEMBL17834019 | 0.85 | ESR1 (0.47) | RAB9ANPC1LMNATSHRMAPK1 | |
| SCHEMBL17834022 | 0.84 | KMT2A (0.47) | RAB9ANPC1TSHRL3MBTL1KMT2A | |
| SCHEMBL17825079 | 0.81 | RAB9A (0.48) | RAB9ANPC1LMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |